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Monday, October 17, 2011

Singapore : Why some are more susceptible to severe forms of dengue

Via Channel News Asia :

" Researchers in South East Asia have identified two genetic variants that provide a clue as to why some people are more susceptible to severe forms of dengue than others.

The study, funded by the Wellcome Trust and the Agency for Science, Technology, and Research (A*STAR), Singapore, was done by comparing genomes of about 2,000 children with severe dengue.

Researchers identified changes in the DNA code located within two genes - MICB on chromosome 6 and PLCE1 on chromosome 10.

They said this appears to increase a child's susceptibility to dengue shock syndrome.

The findings were published on Monday in the journal Nature Genetics."

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