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Thursday, December 9, 2010

CIDRAP : Resistant flu cases underline need for new antivirals

From Robert Roos, CIDRAP news editor, excerpt :

" Dec 8, 2010 : A package of studies and commentary published this week by the Journal of Infectious Diseases points up the ability of influenza viruses to become drug-resistant and continue to spread, highlighting the need for new antivirals.

In one report, US and Canadian researchers identified 28 seasonal H1N1 viruses from 2008 to 2010 that were resistant to the adamantane class of antiviral drugs and to oseltamivir (Tamiflu), one of the two neuraminidase inhibitors licensed in the United States. They found that the dual-resistant viruses became more common during that time.

A second report describes the spread of an oseltamivir-resistant 2009 H1N1 virus in the hematology unit of a British hospital in the fall of 2009, which the authors call the first confirmed episode of its kind. Four of eight patients were found to have contracted the resistant virus from others."

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